| Alone in the Dark: Inferno | Adventure | Eden Studios | Atari | 11/18/2008 |
| Assassin's Creed | Action | Ubisoft Montreal | Ubisoft | 11/14/2008 |
| Assassin's Creed II | Action-Adventure | Ubisoft Montreal | Ubisoft | 11/20/2009 |
| Bioshock | FPS/Survival Horror | 2K Games | 2K Games | 10/21/2008 |
| Dead Space | Horror | EA Redwood Shores | Electronic Arts | 10/30/2008 |
| Fallout 3 | RPG | Bethesda Game Studios | Bethesda Softworks | 10/28/2008 |
| Final Fantasy XIII | RPG | Square Enix | Square Enix | TBA |
| Flower | Poetic Adventure | ThatGameCompany | SCE | 02/12/2009 |
| Fracture | TPS | Day 1 | LucasArts | 10/10/2008 |
| inFamous | | Sucker Punch | Sony | 2009 |
| Killzone 2 | FPS | Guerrilla | SCEE | 2/27/09 |
| LittleBigPlanet | Platform | Media Molecule | Sony Computer Entertainment | 10/21/2008 |
| Mercenaries 2: World in Flames | | Pandemic | EA | 09/05/2008 |
| Metal Gear Solid 4: Guns of the Patriots | Stealth/ Shooter | Kojima Productions | Konami | 06/12/2008 |
| Mirror's Edge | Action Adventure | DICE Sweden | Electronic Arts | 11/11/2008 |
| Mortal Kombat vs. DC Universe | Fighting | Midway Games | Midway Games | 11/16/08 |
| MotorStorm Pacific Rift | Racing | Evolution Studios | Sony | 10/08/2008 |
| Noby Noby Boy | Action | Namco Bandai | Namco Bandai | 02/19/2009 |
| Penny Arcade Adventures: On the Rain-Slick Precipice of Darkness | Adventure | Hothead Games | Hothead Games | 05/21/2008 |
| Prince of Persia | Action/ Adventure | Ubisoft Montreal | Ubisoft | Q4 2008 |
| Resistance 2 | FPS | Insomniac | Sony | 11/4/2008 |
| Spider-Man: Web of Shadows | Action | Shaba Games | Activision | 10/21/2008 |
| Street Fighter IV | Fighting | Capcom | Capcom | TBA |
| Supersonic Acrobatic Rocket-Powered Battle-Cars | Racing | Psyonix Studios | SCE | 02/12/2009 |
| The Lord of the Rings Conquest | Action | Pandemic Studios | Electronic Arts | 01/19/2009 |
| Tom Clancy's Rainbow Six Vegas | Shooter | | Ubisoft | 06/29/2008 |
| Uncharted: Drake's Fortune | Action Adventure | Naughty Dog | SCE | 11/19/2007 |